Ashwagandha Factsheet

What is Ashwagandha?

Ashwagandha (Withania somnifera) is an adaptogenic herb that has been used in Ayurvedic medicine for over 3,000 years. Ashwagandha is known as an adaptogen, for its ability to help the body adapt to stress and promote overall well-being. The root and leaves of the plant are commonly used in supplements due to their high concentration of bioactive compounds that cause the many benefits, including withanolides, alkaloids, and saponins.

What is Ashwagandha good for?

Ashwagandha is known for its adaptogenic and neuroprotective properties, making it beneficial for stress management, cognitive enhancement, hormonal balance, immune support, and physical performance. It is commonly used to reduce anxiety, improve sleep quality, support energy levels, and enhance overall vitality.

What are the benefits of Ashwagandha?

Ashwagandha has been extensively studied for its diverse range of health benefits, including:

  • Stress and Anxiety Reduction: Ashwagandha helps lower cortisol levels, the primary stress hormone, reducing stress responses and promoting relaxation.

  • Cognitive Function: Enhances memory, focus, and mental clarity by supporting neurotransmitter function and reducing oxidative stress in the brain.

  • Physical Performance: Increases endurance, strength, and muscle recovery by reducing exercise-induced muscle damage and boosting energy metabolism.

  • Hormonal Balance: Supports testosterone production in men and helps regulate estrogen and progesterone levels in women, contributing to reproductive health.

  • Sleep Support: Encourages deeper, more restful sleep by modulating stress hormones and supporting relaxation pathways.

  • Immune System Support: Contains antioxidants and immunomodulatory properties that enhance immune response and combat oxidative stress.

Ashwagandha Benefits for Men

  • Supports healthy testosterone levels, which may enhance libido and reproductive health.

  • Increases muscle mass, strength, and athletic performance.

  • Reduces stress-related cortisol, improving mood and resilience.

  • May help prevent premature hair graying and support scalp health.

Ashwagandha Benefits for Women

  • Helps balance reproductive hormones, which may regulate menstrual cycles and reduce PMS symptoms.

  • May alleviate symptoms of menopause, such as hot flashes and mood fluctuations.

  • Promotes healthy skin by reducing oxidative stress and inflammation.

  • Supports relaxation and enhances sleep quality, particularly in women with high stress levels.

Ashwagandha Benefits for Athletes

  • Enhances muscle strength, endurance, and recovery.

  • Improves VO2 max, supporting cardiovascular performance.

  • Reduces muscle damage and inflammation from intense exercise.

  • Supports adrenal function, reducing fatigue and improving energy levels.

Ashwagandha Benefits for Those with Anxiety

  • Lowers cortisol levels, reducing physiological stress responses.

  • Modulates neurotransmitter function to promote calmness and mental stability.

  • Reduces symptoms of generalized anxiety disorder (GAD) and social anxiety.

  • Supports improved sleep, which is critical for mental health and stress resilience.

When should you take Ashwagandha?

The optimal timing for taking ashwagandha depends on your health goals:

  • For Stress and Anxiety Relief: Take ashwagandha midday to help regulate cortisol levels throughout the day and promote a calmer state of mind.
  • For Sleep and Relaxation: Taking ashwagandha in the evening or before bed can enhance sleep quality by promoting relaxation and reducing nighttime cortisol spikes.
  • For Athletic Performance and Recovery: If using ashwagandha for muscle recovery and endurance, it can be taken before workouts to support energy levels or after workouts to aid in recovery.

For best results, take ashwagandha consistently with food to enhance absorption and minimize potential digestive discomfort.

Is Ashwagandha safe?

Ashwagandha is generally well-tolerated and safe when used in appropriate doses. It has a long history of traditional use with minimal adverse effects. However, pregnant or breastfeeding women, individuals with autoimmune diseases, and those taking thyroid or immunosuppressive medications should consult a healthcare professional before use.

Ashwagandha side effects.

While ashwagandha is safe for most people, but since everyone's body is different, some potential side effects with high doses (1g+ a day) include:

  • Mild digestive discomfort, such as nausea or an upset stomach.

  • Drowsiness or sedation at high doses.

  • Potential interactions with thyroid medications or immune-modulating drugs.

  • Rare allergic reactions in sensitive individuals.

As with any supplement, it is best to start with a low dose and assess tolerance before increasing intake. Always consult a healthcare professional before incorporating ashwagandha into your routine, especially if you have underlying health conditions or are taking medications.

Ashwagandha in Our Focase Supplement

Focase contains 250mg of ashwagandha extract, a clinically supported dose that provides cognitive, stress-relief, and energy-boosting benefits without the risk of common side effects seen at higher doses.

Ashwagandha Benefits in Focase

1. HPA Axis Modulation (Stress and Cortisol Regulation)

Ashwagandha helps balance the hypothalamic-pituitary-adrenal (HPA) axis, reducing excessive cortisol production (the stress hormone). This leads to improved stress resilience, lower anxiety, and enhanced mental clarity.

2. GABAergic Activity (Calmness and Anxiety Reduction)

Ashwagandha promotes GABA receptor activity, increasing the calming effects of gamma-aminobutyric acid (GABA), a key inhibitory neurotransmitter. This helps reduce anxiety, stabilize mood, and promote a relaxed yet alert state of mind.

3. Neuroprotection and Cognitive Enhancement

Ashwagandha’s withanolides support nerve regeneration, reduce oxidative stress, and protect against neuroinflammation. This contributes to better focus, memory, and overall cognitive performance.

4. Thyroid and Hormonal Balance

Ashwagandha helps regulate thyroid hormones (T3, T4, and TSH), supporting energy metabolism and brain function. This balance prevents brain fog and fatigue, making it ideal for daily productivity.

5. Adaptogenic Energy Support

Unlike stimulants, ashwagandha works by reducing stress-induced fatigue rather than artificially increasing energy. This results in a natural, sustained boost in mental and physical performance throughout the day.